The meaning and evolution of fever
The evolution of nature has developed towards a stable, organized heat economy (149).
The human being, like all mammals, has its own body-heat balance. Yet there are several ancient animal communities that maintain a system through which they regulate the temperature of their living areas with utmost proirity, thoroughness and in an organized fashion.
The anthill/hive has a central temperature of (15-) 25 (-35) °C depending on the season.
It has complex control by depth, humidity, volume, closure (125).
A wasp nest’s average temperature in summer is approx. 30 °C
The average beehive temperature: 37 °C (25-40 °C)
Controlling constant body temperature in humans
All of our physiological processes are based on the reactions of enzymes that are optimized at a given temperature.
The normal core temperature of humans is constant between 36.5°C and 37.5°C and is independent of the surrounding temperature. It generates heat by burning nutrients, doing muscle work, and by dissipating heat through evaporation and radiating. Neither too high nor too low temperatures favour life processes. The human body is like a controlled heater: boiler, central switch, hot and cold heat sensors and insulation. Insulation is our hair, body hair, skin, and the underlying fat layers. Signals from body temperature sensors reach the cooling and heating centre of the hypothalamus. The central nervous system also senses the temperature of the blood flowing through it. Information also comes from the muscles of the trunk and the cortex. The hypothalamus, as a control centre, sends instructions to the pituitary gland, heart, adrenal glands, striated muscles, and centres of vasodilation.
Body temperature can be influenced by certain factors, such as normal daily fluctuations. In the morning the body temperature is 0.5-1°C lower than in the evening. Thus, in infants and the elderly, a temperature of 37.7°C in the morning is already considered as a rise in temperature, but not in the evening (20). See the section on the meaning of fever. During intense exercise (wood cutting (137), sports, hot yoga, long crying spells in children...) or heat gut/sunstroke, body heat can rise up to 39°C. This is more like heat congestion, because the heat that the body produces can only be released more slowly than the rare at which it is produced.
The daily fluctuation of body temperature is 0.5-1.0°C. It reaches its lowest level between 1 am - 4 am and the maximum between 4 pm - 7 pm. That is why fever also develops in the evening and goes down by dawn.
Positive effects of fever. How does this work in the evolution of animals?
In the case of an external attack, the elevated temperature (for both individual and social organizations) increases the chances of survival. With all its apparent disadvantages, fever has become ubiquitous in advanced organisms during evolution (3, 13, 149).
Even unicellular organisms look for a warmer place in the event of a viral attack.
Insects (ants, wasps, bees) that make up the community also try to create a higher temperature than their surroundings in reaction to attacks.
Some guppies, when attacked by a parasitic worm (Gyrodactylus turnbulli), exhibit a so-called behavioural fever, that is, they swim to a warmer place in the water and remain there for a while until the parasites die (126).
In several animal studies, with very few exceptions, morbidity and mortality were increased when fever was reduced physically or medicinally in warm-blooded animals; or by preventing cold-blooded animals from accessing heat (55, 86).
If mammals get a high fever early in dangerous infections, it increases survival rates (12-14).
Fever can be called an independent functional health maintenance and healing system of the warm-blooded. A positive, useful coping strategy, exercise and learning (148-150).
So let's trust it, let it work and do its job!
Do not disturb or hinder, simply accompany it.
Refer to the literature by numbers in this document here: ReferencesVersion update 08th March 2020