Vaccination and fever

What about fever and vaccines?

Before vaccination

Although a mild infection or even an elevation in temperature is not a contraindication to vaccination, professional sources state that it is recommended a child should be free from fever and healthy for at least one week before a vaccination. If there are people with infectious diseases in the child’s surroundings and an infection might be lurking in him as well, it is best to wait a couple of days for the situation to clear up.


After the vaccination

In approximately half of all cases, children respond to vaccines with an elevated temperature or fever. This is a natural reaction indicating that the child is producing antibodies against the pathogens.

According to some scientific studies it seems to be more immunologically beneficial if we do not routinely administer antipyretic or analgesic drugs. Anti-fever and anti-pain agents reduce the production of immunological antibodies. Thus, the immune response that the vaccine wishes to achieve is reduced (138,139,140,141,151). Other studies contradict this somewhat (142,143).

The results also depend on the vaccine used, how old the children who have been vaccinated were, how many times they have been vaccinated and when antipyretic drugs are used, and which ones.



Do not administer antipyretic and analgesic agents routinely either before or after vaccination. 

In the case of very high fever and injection site swelling, redness (local inflammation), analgesic agents may be considered (140,144)

In such a case consult your physician.


Refer to the literature by numbers in this document here: References

Version update 03 October 2020